What is 4-CMC?
4-CMC (4-Chloromethcathinone) is a synthetic stimulant belonging to the cathinone class, closely related to other compounds such as mephedrone. It is characterized by the substitution of a chlorine atom at the para position of the phenyl ring, which influences its pharmacological properties.
Chemical Properties:
- Chemical Formula: C10H12ClNO
- Molecular Weight: 197.66 g/mol
- IUPAC Name: 1-(4-chlorophenyl)-2-(methylamino)propan-1-one
4-CMC is known for its stimulant effects, primarily acting as a serotonin–norepinephrine–dopamine releasing agent (SNDRA), which leads to increased concentrations of these neurotransmitters in the central nervous system.
Chemical Class of 4-CMC
4-CMC belongs to the cathinone chemical class, a group of compounds recognized for their stimulant properties. Cathinones are β-keto analogs of amphetamines, sharing a similar core structure with a ketone functional group at the β position.
Structural Characteristics:
- The addition of a chlorine atom to the para position of the phenyl ring distinguishes 4-CMC from other cathinones and contributes to its unique pharmacological profile.
- This structural modification influences 4-CMC’s ability to release serotonin, norepinephrine, and dopamine, leading to its stimulant effects.
Researchers studying psychostimulants and their effects on neurotransmitter systems may find 4-CMC to be a valuable compound due to its unique properties and potency.




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